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HPE ProLiant DL380 Gen11 16 Core 2.1GHz Rack Server Intel Xeon Gold 5416S, 32GB Smart Memory

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Product details

Management number 241235548 Release Date 2026/07/17 List Price $4,302.30 Model Number 241235548
Category
Overview

The HPE P52561-B21 is a rack server designed to deliver robust performance for demanding business applications. Powered by a 16-core Intel Xeon Gold 5416S processor running at 2.1 GHz and equipped with 32GB of DDR5 Smart Memory at 4800 MT/s, it ensures smooth multitasking and fast data processing. Its 2U form factor fits standard data center racks, making it a practical choice for enterprise environments that require scalable computing power and flexible storage options.

Key features
  • Processor with 16 cores providing strong multi-threaded performance for complex workloads
  • 32GB DDR5 Smart Memory that supports fast and reliable data access to keep operations responsive
  • Broadcom MR408i-o storage controller managing up to eight Small Form Factor drives for versatile storage configurations
  • Eight PCIe Gen5 slots and two OCP 3.0 slots allowing expansion with additional network or storage cards as business needs evolve
  • Four standard cooling fans designed to maintain optimal operating temperatures under heavy use
  • 800W Flex Slot Platinum hot-plug power supply enabling reliable power delivery and easy replacement without downtime
  • Embedded HPE iLO Standard for remote monitoring and management, simplifying server administration
  • Security features including TPM 2.0, optional locking bezel, and intrusion detection to protect hardware and data integrity
  • 3-year warranty covering parts, labor, and onsite support to ensure long-term reliability and peace of mind
Key specs
  • Processor: Intel Xeon Gold 5416S, 16 cores, 2.1 GHz
  • Memory: 32GB DDR5 Smart Memory, 4800 MT/s
  • Storage controller: Broadcom MR408i-o
  • Drive support: Up to 8 Small Form Factor drives
  • Expansion slots: 8 PCIe Gen5, 2 OCP 3.0
  • Cooling: 4 standard fans
  • Power supply: 800W Flex Slot Platinum hot-plug
  • Form factor: 2U rack mount
  • Security: TPM 2.0, optional locking bezel, intrusion detection
  • Warranty: 3 years parts, labor, onsite support
Connectivity and compatibility

This server offers extensive expansion capabilities through its eight PCIe Gen5 slots and two OCP 3.0 slots, supporting a wide range of network and storage peripherals. The Broadcom MR408i-o controller ensures efficient management of multiple Small Form Factor drives, allowing you to tailor storage performance and capacity to your specific workload requirements. Its 2U rack design fits seamlessly into standard data center environments, making it compatible with existing infrastructure.

Performance and reliability

With a 16-core Intel Xeon Gold processor and high-speed DDR5 memory, this server handles multi-threaded applications and virtualization tasks with ease. The four cooling fans maintain stable temperatures during intensive operations, while the 800W Flex Slot Platinum power supply provides consistent and redundant power delivery. Security features like TPM 2.0 and intrusion detection help safeguard your system against unauthorized access and hardware tampering.

Ideal uses and environments

This server is well suited to enterprise data centers, virtualization hosts, and businesses that require a balance of processing power, storage flexibility, and manageability. It supports workloads that demand consistent performance and scalable hardware options, making it a strong choice for IT teams managing growing infrastructure or deploying mission-critical applications.


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